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. 2022 Aug 10;23(1):98. doi: 10.1186/s10194-022-01469-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — The expression of the dopamine D1 and D2 receptors in CM rats. A, The DRD2 mRNA level was markedly lower in the CM group than in the Sham group, while significant differences in DRD1 mRNA expression were not observed. B and C, The DRD2 protein level in the CM group was statistically decreased compared to that in the Sham group. Two-tailed Student’s t test; n = 6/group; ***P < 0.001 vs. the Sham group. D DRD2 (red; 78.9 ± 2.2%) and GLUA1-containing AMPARs (green; 70.7 ± 6.5%) were colocalized in the TNC in CM rats (scale bar = 20 μm; n = 6/group)