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. 2022 Jul 22;10:882416. doi: 10.3389/fped.2022.882416

Table 4.

Comparison of antibiotic use (A) and “rule out sepsis” evaluations (B) as per SCO vs. recommendations of the NSC in the study population. Differences between proportions were analyzed using McNemar's test.

NSC
No antibiotics Antibiotics Total (% of study cohort)
(A) Comparison of antibiotic use
SCO No antibiotics 3,254 126 3,380 (98.1)
Antibiotics 5 60 65 (1.9)
Total (% of study cohort) 3,259 (94.6) 186 (5.4) 3,445 (100.0)
NSC
No test Rule out sepsis Total (% of study cohort)
(B) Comparison of “rule out sepsis” evaluations
SCO Not evaluated 3,231 76 3,307 (96.0)
Rule out sepsis 20 118 138 (4.0)
Total (% of study cohort) 3,251 (94.4) 194 (5.6) 3,445 (100.0)

NSC, neonatal sepsis calculator; SCO, serial clinical observation.