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. 2022 Aug 9;23:50. doi: 10.1186/s12868-022-00733-9

Fig. 3.

Fig. 3

Increased expression of GSDMD in ventral horn neurons of ALS mice lumbar spinal cord. Double immunofluorescence staining showed that GSDMD (red) /NeuN (green) double-positive neurons were first observed at 60 d, 95 d of age in the ventral horn of ALS mice a, b. With disease progression, GSDMD positive signal was observe in glial cells at 108 d and 122 d of ALS mice c, d. Arrows indicate double-labelled cells. Scale bar = 50 μm