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. 2022 Aug 10;28(11):1531–1535. doi: 10.1016/j.jiac.2022.08.004

Table 2.

Clinical characteristics on admission in the Delta and Omicron variant predominant periods by age group.

Patient characteristics Total <3 months 3 to <24 months 2 to <6 years 6 to <13 years ≥13 years
Number of cases
 Delta predominant period 458 20 74 88 142 134
 Omicron predominant period 389 27 86 67 116 93
Asymptomatic cases
 Delta predominant period 61 (13.3) 3 (15.0) 14 (18.9) 17 (19.3) 23 (16.2) 4 (3.0)
 Omicron predominant period 18 (4.6) 1 (3.7) 5 (5.8) 9 (13.4) 1 (0.9) 2 (2.2)
Body temperature (°C)
 Delta predominant period 37.2 (36.7–37.9) 37.5 (37.1–38.0) 37.2 (36.7–37.7) 37.1 (36.7–37.7) 37.0 (36.7–37.6) 37.2 (36.8–38.0)
 Omicron predominant period 37.5 (36.9–38.5) 37.6 (37.2–38.3) 37.6 (37.0–38.9) 37.8 (37.0–38.5) 37.7 (36.9–38.5) 37.2 (36.8–38.1)
Fever ≥ 38.0°C
 Delta predominant period 109 (23.8) 7 (35.0) 22 (29.7) 18 (20.5) 27 (19.0) 35 (26.1)
 Omicron predominant period 145 (37.3) 9 (33.3) 38 (44.2) 29 (43.3) 43 (37.1) 26 (28.0)
SpO2 < 96% under room air
 Delta predominant period 18 (4.1) 1 (5.6) 4 (5.6) 4 (4.8) 3 (2.1) 6 (4.7)
 Omicron predominant period 16 (4.3) 1 (3.7) 4 (4.9) 2 (3.2) 5 (4.5) 4 (4.5)
Runny nose
 Delta predominant period 108 (23.6) 8 (40.0) 29 (39.2) 17 (19.3) 26 (18.3) 28 (20.9)
 Omicron predominant period 91 (23.4) 10 (37.0) 33 (38.4) 17 (25.4) 14 (12.1) 17 (18.3)
Sore throat
 Delta predominant period 85 (18.6) N/A 3 (4.1) 5 (5.7) 26 (18.3) 51 (38.1)
 Omicron predominant period 89 (22.9) N/A 0 (0.0) 3 (4.5) 30 (25.9) 56 (60.2)
Cough
 Delta predominant period 215 (46.9) 6 (30.0) 26 (35.1) 40 (45.5) 60 (42.3) 83 (61.9)
 Omicron predominant period 191 (49.1) 10 (37.0) 50 (58.1) 30 (44.8) 54 (46.6) 47 (50.5)
Wheezing
 Delta predominant period 6 (1.3) N/A 2 (2.7) 4 (4.5) 0 (0.0) 0 (0.0)
 Omicron predominant period 11 (2.8) N/A 6 (7.0) 4 (6.0) 1 (0.9) 0 (0.0)
Chest pain
 Delta predominant period 8 (1.7) N/A 0 (0.0) 0 (0.0) 2 (1.4) 6 (4.5)
 Omicron predominant period 2 (0.5) N/A 0 (0.0) 1 (1.5) 0 (0.0) 1 (1.1)
Fatigue
 Delta predominant period 81 (17.7) N/A 6 (8.1) 2 (2.3) 17 (12.0) 56 (41.8)
 Omicron predominant period 49 (12.6) N/A 2 (2.3) 7 (10.4) 20 (17.2) 20 (21.5)
Headache
 Delta predominant period 72 (15.7) N/A 1 (1.4) 3 (3.4) 15 (10.6) 53 (39.6)
 Omicron predominant period 46 (11.8) N/A 0 (0.0) 5 (7.5) 16 (13.8) 25 (26.9)
Alteration of consciousness
 Delta predominant period 4 (0.9) 0 (0.0) 0 (0.0) 2 (2.3) 1 (0.7) 1 (0.7)
 Omicron predominant period 8 (2.1) 0 (0.0) 0 (0.0) 1 (1.5) 5 (4.3) 2 (2.2)
Seizures
 Delta predominant period 9 (2.0) 0 (0.0) 3 (4.1) 2 (2.3) 3 (2.1) 1 (0.7)
 Omicron predominant period 24 (6.2) 0 (0.0) 6 (7.0) 9 (13.4) 9 (7.8) 0 (0.0)
Diarrhea
 Delta predominant period 38 (8.3) 0 (0.0) 9 (12.2) 7 (8.0) 10 (7.0) 12 (9.2)
 Omicron predominant period 22 (5.7) 1 (3.7) 5 (5.8) 2 (3.0) 11 (9.5) 3 (3.2)
Vomiting
 Delta predominant period 39 (8.5) 2 (10.0) 5 (6.8) 7 (8.0) 9 (6.3) 16 (11.9)
 Omicron predominant period 65 (16.7) 2 (7.4) 10 (11.6) 13 (19.4) 32 (27.6) 8 (8.6)
Dysgeusia
 Delta predominant period 28 (6.1) N/A 0 (0.0) 1 (1.1) 9 (6.3) 18 (13.4)
 Omicron predominant period 3 (0.8) N/A 0 (0.0) 0 (0.0) 1 (0.9) 2 (2.2)
Olfactory dysfunction
 Delta predominant period 26 (5.7) N/A 0 (0.0) 0 (0.0) 8 (5.6) 18 (13.4)
 Omicron predominant period 0 (0.0) N/A 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Arthralgia/myalgia
 Delta predominant period 25 (5.5) N/A 0 (0.0) 0 (0.0) 2 (1.4) 23 (17.2)
 Omicron predominant period 12 (3.1) N/A 0 (0.0) 1 (1.5) 4 (3.4) 7 (7.5)
Rash
 Delta predominant period 9 (2.0) 1 (5.0) 5 (6.8) 2 (2.3) 1 (0.7) 0 (0.0)
 Omicron predominant period 9 (2.3) 1 (3.7) 2 (2.3) 3 (4.5) 2 (1.7) 1 (1.1)

SpO2, saturated oxygen in arterial blood.

Subjective symptoms in children under 3 months were not applicable (N/A) because they had difficulty describing them.

Symptom frequencies by age between the Delta and Omicron variant predominant periods were compared using the Fisher exact test for categorical variables and Mann-Whitney U test for continuous variables; items with P < 0.05 are in bold.