Table 3.
Comparison of severity, complications, and outcomes between the Delta variant and Omicron variant predominant periods.
| Variables | Total | Delta variant predominant period | Omicron variant predominant period | P value |
|---|---|---|---|---|
| Case number | 847 | 458 | 389 | NA |
| Noninvasive oxygen support (nasal cannula, face mask, reservoir mask, high-flow oxygen device) | 45 (5.3) | 17 (3.7) | 28 (7.2) | 0.031 |
| Invasive mechanical ventilation/ECMO | 2 (0.2) | 0 (0.0) | 2 (0.5) | 0.211 |
| ICU admission | 13 (1.5) | 7 (1.5) | 6 (1.5) | 1.0 |
| Pneumonia | 9 (1.8) | 2 (0.4) | 7 (1.8) | 0.088 |
| Meningitis/encephalitis | 1 (0.1) | 0 (0.0) | 1 (0.3) | 0.782 |
| Seizures as complication | 8 (0.9) | 2 (0.4) | 6 (1.5) | 0.153 |
| Myocarditis/endocarditis/cardiomyopathy | 2 (0.2) | 1 (0.2) | 1 (0.3) | 1.0 |
| Length of hospital stay (days), median (IQR) | 7.0 (4.0–9.0) | 7.0 (5.0–9.0) | 5.0 (3.0–8.0) | <0.001 |
| Death | 0 (0.0) | 0 (0.0) | 0 (0.0) | NA |
ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit; IQR, interquartile range; NA, not applicable; VOC, variant of concern.