FIGURE 2.
Set of images of 73-y-old patient after radiation therapy (initial PSA, 16 ng/mL; biopsy Gleason score, 8; pT2c) and concurrent androgen hormone treatment, currently presenting for rising PSA value (6.27 ng/mL). After enrollment, patient was randomized to oral ingestion arm and received 18.9 g of MSG before second 68Ga-PSMA-11 injection. PSMA PET/CT images revealed multifocal prostate involvement, common iliac right and external iliac right pelvic lymph nodes, and multiple bone lesions. Maximum-intensity-projection images show overall decline in 68Ga-PSMA-11 accumulation within normal organs as well as tumor lesions on MSG scan relative to control scan. Axial view images display relevant case example of bone lesion with significant PSMA decrease after MSG administration (SUVmax from 18.6 to 9.2). p.i. = after injection.