TABLE 3.

Comparison of ⁶⁸Ga-PSMA11 Uptake in Normal Organs in Control and MSG Scans

	SUVmean				SUVmax
Site	Control	MSG	Change	P	Control	MSG	Change	P
Oral ingestion (n = 8)
Lacrimal glands	5.5 ± 2.3	2.6 ± 0.9	−50.9% ± 6.5%	0.001	9.9 ± 4.7	4.3 ± 1.6	−55.5% ± 6.1%	0.002
Parotid glands	10.9 ± 4.1	6.9 ± 3.3	−32.9% ± 22.6%	0.002	19.0 ± 6.6	13.2 ± 6.2	−34.1% ± 21.7%	0.020
Submandibular glands	15.9 ± 5.7	6.6 ± 2.5	−58.9% ± 8.9%	<0.001	29.0 ± 10.5	10.4 ± 3.7	−63.2% ± 9.9%	<0.001
Salivary glands	12.1 ± 4.6	6.8 ± 3.1	−45.5% ± 14.6%	0.004	29.0 ± 10.5	13.5 ± 5.9	−53.4% ± 11.1%	<0.001
Liver	4.6 ± 0.5	2.1 ± 0.3	−54.2% ± 5.3%	<0.001	10.7 ± 1.3	5.5 ± 0.4	−50.1% ± 8.3%	<0.001
Spleen	8.1 ± 2.0	3.0 ± 0.9	−62.8% ± 6.9%	<0.001	13.7 ± 3.5	5.3 ± 1.5	−61.5% ± 8.6%	<0.001
Kidney	34.5 ± 14.8	17.4 ± 8.8	−51.5% ± 13.7%	<0.001	63.6 ± 25.0	32.7 ± 16.6	−51.3% ± 13.3%	<0.001
Urinary bladder	16.0 ± 8.7	69.1 ± 34.3	+371.6% ± 300.2%	0.004	33.7 ± 23.9	184.2 ± 97.5	+593.2% ± 659.5%	0.003
Total tumor lesions	6.6 ± 3.5	3.5 ± 2.1	−45.0% ± 19.0%	0.023	21.5 ± 19.8	8.2 ± 8.7	−55.7% ± 22.0%	0.061
Swishing (n = 8)
Lacrimal glands	6.5 ± 1.6	6.0 ± 2.5	+4.9% ± 22.0%	0.625	12.3 ± 3.2	11.1 ± 4.6	−5.2% ± 25.0%	0.556
Parotid glands	11.7 ± 2.2	12.0 ± 2.7	+0.1% ± 8.4%	0.917	22.2 ± 6.1	22.5 ± 6.0	+1.9% ± 10.4%	0.792
Submandibular glands	12.8 ± 3.5	13.4 ± 3.6	+5.6% ± 6.8%	0.061	21.3 ± 7.0	22.6 ± 7.3	+7.7% ± 11.6%	0.188
Salivary glands	11.5 ± 2.3	11.9 ± 2.9	+1.6% ± 7.8%	0.521	25.8 ± 6.0	26.6 ± 7.2	+4.3% ± 12.3%	0.442
Liver	4.1 ± 0.8	4.3 ± 0.9	+5.7% ± 17.3%	0.317	9.8 ± 1.3	10.4 ± 3.0	+5.3% ± 15.7%	0.321
Spleen	6.1 ± 2.0	6.3 ± 1.7	+6.2% ± 18.6%	0.458	10.8 ± 3.9	10.1 ± 2.6	−0.3% ± 15.2%	0.622
Kidney	30.1 ± 8.0	30.1 ± 5.8	+ 1.9% ± 13.9%	0.958	57.1 ± 15.9	57.6 ± 13.6	+3.4% ± 15.8%	0.782
Urinary bladder	20.2 ± 13.5	24.2 ± 8.3	+36.5% ± 41.4%	0.357	50.6 ± 42.4	56.4 ± 20.2	+52.0% ± 70.0%	0.651
Total tumor lesions	4.9 ± 1.1	5.4 ± 1.6	7.8% ± 13.8%	0.125	12.5 ± 7.7	15.0 ± 11.3	12.6% ± 27.8%	0.196

Data are average ± SD.