Multiple parameter MRI assessment of thermal HIFU ablation of uterine fibroids. Patient 31 (52 years old, intramural leiomyoma). Coronal images at the treatment plane pre- and post-HIFU ablation. (a) Contrast-enhanced T1-weighted image acquired pretreatment. (b) DW image acquired pretreatment. (c) T2-weighted image acquired pretreatment. (d) ADC map pretreatment (ADC value: ). (e) Contrast-enhanced T1-weighted image acquired posttreatment. The area of the resulting nonperfused region (demarcated with a light grey line in pane e) was 20.8 cm2. The thermal dose estimate calculated from the temperature maps is shown in the inset figure, at the upper right corner. Areas that reached a thermal dose of 240 min are grey, and areas that reached a thermal dose of 18 min are white. The area of the region with a thermal dose exceeding 18 min at 43°C was 14.7 cm2. (f) DW image acquired posttreatment. The area of the resulting hyperintense region (outlined with a light grey line in pane f) was 22.8 cm2. (g) T2-weighted image acquired posttreatment, the affected area appears hyperintense (h) ADC map posttreatment, the affected area appears hypointense (ADC value: ). Figure adapted from [8].