Figure 7.

Pre, peri, and postprocedure ultrasound imaging of histotripsy ablation in the liver in a preclinical model. Images show the histotripsy liver treatment monitored by ultrasound imaging before (a), during (b), and after (c) treatment. Prior to each treatment, the bubble cloud was generated in free water with the free-field focal location marked as an “x” on the ultrasound image (a). The histotripsy bubble cloud appears as a dynamically changing hyperechoic region on ultrasound imaging (b) while the resulting lesion appears hypoechoic (c) resulting from fractionation of liver parenchyma. Figure adapted from [19].