Table 5.

Linear regression models for ALSFRSR at study entry and blood parameters.

	Univariate analysis			Multivariate analysis*			ALSFRSR ↓
Variable	n	p -value	95% CI	n	p- value	95% CI
CK	803	<0.001	(0.003, 0.008)	747	0.001	(0.002, 0.007)	CK↓
Albumin	518	<0.001	(4.073, 6.947)	482	<0.001	(3.964, 7.035)	Alb↓
Creatinine	974	<0.001	(3.965, 7.68)	904	<0.001	(3.664, 7.605)	Crea↓
Total cholesterol	690	0.385	(−0.007, 0.018)	651	0.371	(−0.007, 0.019)
HDL	607	0.044	(0.001, 0.075)	564	0.044	(0.001, 0.079)	HDL↓
LDL	603	0.395	(−0.023, 0.009)	563	0.462	(−0.022, 0.01)
Triglyceride	656	0.097	(−0.017, 0.001)	612	0.061	(−0.019, 0.000)

^* Controlled for gender, age at diagnosis, diagnostic delay, region of onset, UMN and LMN involvement.

Bold values show p-values < 0.05.