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. 2022 Jul 22;13:952338. doi: 10.3389/fimmu.2022.952338

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Copyright © 2022 Su, Zhang, Yang, Tang, Shen, Liu, Ji, Maurer and Jiao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Blood levels of Gal-9 and TIM-3-positive T cells are markedly increased in patients with AD. (A) Serum Gal-9 levels of patients with atopic dermatitis involved in this study (AD, n = 30), as compared to healthy controls (HC, n = 30), (B) the percentage of CD4⁺TIM-3⁺ T cells in whole blood, the percentage of (C) TIM-3⁺T_H1 cells and (D) TIM-3⁺T_H17 cells in PBMCs of the above patients with AD compared to HC. These results are presented as means ± SEM.