Table 2.
Event of Interest | ≥ Grade 3 | Any Grade |
---|---|---|
Hematologic AEs, no. (%) | ||
Thrombocytopenia | 8 (24) | 20 (59) |
Anemia | 6 (18) | 19 (56) |
Neutropenia | 4 (12) | 13 (38) |
Lymphocyte count increased | 2 (6) | 10 (29) |
Lymphopenia | 4 (12) | 9 (27) |
Non-hematologic AEs, no. (%) | ||
Fatigue | 0 (0) | 19 (56) |
Nausea | 1 (3) | 18 (53) |
Anorexia | 0 (0) | 14 (41) |
Diarrhea | 2 (6) | 14 (41) |
Hypertension | 6 (18) | 12 (35) |
Joint/Bone Pain | 1 (3) | 12 (35) |
Hyponatremia | 5 (15) | 10 (29) |
Pneumonia | 3 (9) | 9 (27) |
Hyperglycemia | 2 (6) | 9 (27) |
Weight Loss | 0 (0) | 9 (27) |
Fall | 2 (6) | 5 (15) |
Bleeding* | 0 (0) | 4 (12) |
Cataract | 2 (6) | 4 (12) |
Cognitive Disturbance | 2 (6) | 4 (12) |
Hypophosphatemia | 2 (6) | 4 (12) |
Arthralgia | 0 (0) | 3 (9) |
Atrial Fibrillation | 0 (0) | 3 (9) |
Death | 3 (9) | 3 (9) |
Hypoxia | 2 (6) | 2 (6) |
Grade 1/2 epistaxis (n=2), hematuria (n=1), menorrhagia (n=1)