TABLE 2.
Regional VT in Test Scans
| Regional VT (mL/cm3) |
Minimum scan duration (min) |
|||||||
|
11C-EKAP (n = 6) |
11C-FEKAP (n = 6) |
11C-EKAP (n = 6) | 11C-FEKAP (n = 6) | |||||
| Region | 1TC | 2TC | MA1 | 1TC | 2TC | MA1 | MA1 | MA1 |
| Amygdala | 19.9 (22%) | 18.1* (6%) | 21.6 (25%) | 9.1 (33%) | 9.0† (39%) | 9.6 (36%) | 90 | 90 |
| Insula | 13.9 (21%) | 14.7 (19%) | 15.2 (21%) | 6.4 (27%) | 6.8‡ (31%) | 7.1 (28%) | 80 | 70 |
| Anterior cingulate cortex | 13.1 (13%) | 13.8 (13%) | 14.2 (14%) | 5.8 (21%) | 6.2 (22%) | 6.5 (23%) | 70 | 70 |
| Globus pallidus | 10.7 (19%) | 11.5 (18%) | 11.7 (19%) | 4.6 (28%) | 5.3 (29%) | 5.4 (30%) | 70 | 60 |
| Temporal cortex | 9.8 (18%) | 11.0 (21%) | 10.7 (18%) | 4.3 (25%) | 4.8 (27%) | 5.0 (28%) | 80 | 90 |
| Putamen | 9.3 (18%) | 10.8 (21%) | 10.3 (18%) | 3.9 (23%) | 4.6 (26%) | 4.8 (26%) | 80 | 100 |
| Frontal cortex | 9.0 (19%) | 10.3 (23%) | 9.9 (19%) | 4.1 (25%) | 4.6 (27%) | 4.8 (27%) | 80 | 90 |
| Hippocampus | 7.6 (21%) | 9.1 (26%) | 8.8 (22%) | 3.2 (23%) | 3.8 (27%) | 4.1 (27%) | 80 | 90 |
| Occipital cortex | 7.5 (20%) | 8.7 (21%) | 8.3 (19%) | 3.2 (26%) | 3.8 (29%) | 3.9 (30%) | 80 | 90 |
| Caudate | 7.5 (24%) | 8.1 (26%) | 8.0 (24%) | 2.9 (27%) | 3.4 (29%) | 3.5 (30%) | 50 | 80 |
| Posterior cingulate cortex | 6.8 (27%) | 7.2‡ (25%) | 7.6 (26%) | 2.7 (29%) | 3.1 (30%) | 3.3 (30%) | 80 | 100 |
| Cerebellum | 5.7 (32%) | 6.6 (29%) | 6.4 (29%) | 2.1 (34%) | 2.6‡ (32%) | 3.0 (37%) | 80 | 100 |
| Thalamus | 4.8 (20%) | 5.2‡ (15%) | 5.4 (20%) | 1.5 (22%) | 1.9‡ (20%) | 2.3 (39%) | 80 | 110 |
*
n = 4 (relative SE > 10% was excluded).
†
n = 2 (relative SE > 10% was excluded).
‡
n = 5 (relative SE > 10% was excluded).
Data in parentheses are percentage coefficient of variation across subjects.