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. 2022 Jul 27;13:912138. doi: 10.3389/fmicb.2022.912138

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Copyright © 2022 Corrêa, Faffe, Galliez, Gonçalves, Maia, da Silva, Moreira, Mariani, Campos, Leitão, de Souza, Cunha, Nascimento, Ribeiro, da Cruz, Policarpo, Gonzales, Rodgers, Berg, Vijesurier, Cloherty, Hackett Jr., Ferreira Jr., Castiñeiras, Tanuri and da Costa.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of the UFRJ-CTD cohort from 20 August to 21 September and sample selection. Mildly symptomatic individuals tested for severe acute respiratory syndrome-related coronavirus (SARS-CoV-2) diagnosis at the Center for COVID-19 Diagnosis of Federal University of Rio de Janeiro from August 2020 to September 2021 account for a total of 8.095 RT-qPCR and antigen RTD exams. Of this total, 1.820 tested positive for SARS-CoV-2 1.539 also being antigen RDT positive (concordant samples) and 293 antigen RDT negative (discordant samples). From this group, 61 samples (23 concordant and 29 discordant) were selected for further studies comprising the cross-sectional dataset while 30 additional patients were selected for the follow-up dataset where the patient has a second sample collected with a minimum of 6 days after diagnosis.