Table 1:

Therapeutic potentials of salvinorin A and its analogues.

Compound	Therapeutic Potential
Salvinorin A	Analgesic [31], addiction therapy [32], anti-cocaine seeking therapy [33], antidepressant [32], antipruritic [34], stroke rescue [25,28,35]
Salvindolin	Antidepressant [11], analgesic [11]
PR-38	Colitis [36], irritable bowel syndrome [37], antipruritic [38]
1α-Hydroxysalvinorin A	Anxiolytic [15], cocaine withdrawal therapy [15]
RB-64	Analgesic [8]
Salvidenin	Analgesic [3], anxiolytic [3]
16-Ethynyl salvinorin A	Analgesic [13], attenuation of cocaine-induced reinstatement [39]
16-Bromo salvinorin A	Analgesic [13], attenuation of cocaine-induced reinstatement [39]
β-Tetrahydropyran salvinorin B	Analgesic [26], anti-inflammatory [26], cocaine withdrawal therapy [40], addiction therapy [40]
Herkinorin	Anti-inflammatory [41], stroke rescue [42]