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. 2022 Aug 6;15:1549–1559. doi: 10.2147/CCID.S367347

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© 2022 Kuai and Jian.

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RIPK1 was regulated by miR-23b-3p/A20 axis. (A) The mRNA expression of RIPK1 in keloid tissues. (B) The correlation between the expression of A20 and RIPK1. The mRNA and protein expression of RIPK1 in TGF-β1-treated primary KFs (C) and TGF-β1-treated KEL FIB cells (D). The mRNA and protein expression of RIPK1 in primary KFs with co-transfection (E) and KEL FIB cells with co-transfection (F). ***P<0.001.

Abbreviations: inhibitor NC, negative control inhibitor; si-NC, negative control siRNA; inhibitor, miR-23b-3p inhibitor; si-A20, siRNA against TNFAIP3.