Table 2. Concentrations of selected proteins in Tasso SST serum samples from healthy controls recruited at TAMC (supervised collection in-clinic with prompt processing) and NHRC (at-home self-collection with delayed processing).

Up to 5 samples were collected from each subject over a 28-day period and are aggregated here. Concentrations are given as the median and interquartile range, with Mann-Whitney U test q-values for comparing the two sites. *Note the high proportion of at-home, self-collected samples with D-dimer concentrations above the ULoQ.

Healthy control Tasso SST serum—Comparison between sampling protocols
	Clinic supervised	Home self-collection	MW U test
Analyte	TAMC (n = 196)	NHRC (n = 44)	q-value
Ferritin	100 ng/ml (59–158)	72 ng/ml (52–212)	0.707
CRP	0.88 μg/ml (0.43–2.04)	1.18 μg/ml (0.37–2.64)	0.568
CD163	433 ng/ml (322–566)	457 ng/ml (373–531)	0.442
TNF-R1	0.97 ng/ml (0.83–1.11)	0.99 ng/ml (0.84–1.18)	0.442
RAGE	0.91 ng/ml (0.75–1.14)	1.01 ng/ml (0.76–1.24)	0.396
VEGF-A	153 pg/ml (91–244)	196 pg/ml (112–279)	0.118
IL-6	1.53 pg/ml (0.91–2.39)	1.70 pg/ml (1.46–2.32)	0.080
ICAM-1	290 ng/ml (248–339)	261 ng/ml (249–294)	0.027
IL-18BPa	4.27 ng/ml (3.78–5.56)	4.05 ng/ml (3.27–4.57)	0.009
CXCL10	113 pg/ml (88–167)	97 pg/ml (83–130)	0.007
IL-1Ra	1.57 ng/ml (1.11–2.09)	2.24 ng/ml (1.74–4.12)	6.3E-06
IL-6Ra	45.2 ng/ml (37.7–51.9)	34.1 ng/ml (28.2–44.2)	3.1E-06
LCN	77.1 ng/ml (64.9–93.3)	106.7 ng/ml (81.1–162.9)	2.1E-06
PCT	60.8 pg/ml (40.7–81.3)	37.8 pg/ml (33.7–44.8)	4.5E-07
IL-5	0.13 pg/ml (0–0.28)	0.39 pg/ml (0.22–0.64)	1.2E-08
D-dimer*	0.23 μg/ml (0.12–0.48)	12.19 μg/ml (5.61–463.5)	1.9E-15
IL-1B	0.02 pg/ml (0–0.44)	2.30 pg/ml (0.95–4.25)	1.9E-15