Table 1.
Prior treatment | |||||||||
---|---|---|---|---|---|---|---|---|---|
Patient | Sex | Age | KPS | Standard therapy | Second-line | Third-line | Dose (vp) | Resection | IDH status |
1 | F | 42 | 90 | Resection, RT/TMZ, aTMZ | Bevacizumab + lomustine | 107 | Yes | Wild-type | |
2 | F | 29 | 90 | Resection, RT/TMZ, aTMZ | Bevacizumab + lomustine | 107 | No | n/a | |
3 | M | 54 | 80 | Resection, RT | Temsirolimus | Bevacizumab + lomustine | 107 | No | Wild-type |
4 | F | 46 | 90 | Resection, RT/TMZ, aTMZ | Lomustine | 108 | No | Wild-type | |
5 | M | 53 | 100 | Resection, RT/TMZ, aTMZ | Bevacizumab + lomustine | 108 | No | Wild-type | |
6 | F | 60 | 90 | Resection, RT, TMZ | 108 | Yes | Wild-type | ||
7 | M | 67 | 80 | Resection, RT/TMZ | Dasatinib + lomustine | 109 | No | Wild-type | |
8 | M | 64 | 90 | Resection, RT/TMZ, aTMZ | Lomustine | 109 | No | n/a | |
9 | M | 60 | 90 | Resection, RT/TMZ | DC therapy | Lomustine | 109 | No | n/a |
10 | F | 54 | 90 | Biopsy, RT, TMZ | Lomustine | 1010 | No | Wild-type | |
11 | F | 48 | 80 | Resection, RT/TMZ | Re-resection, aTMZ | 1010 | No | Wild-type | |
12 | M | 52 | 90 | Resection, RT/TMZ, aTMZ | 1010 | Yes | Wild-type | ||
13 | M | 45 | 90 | Resection, RT/TMZ, aTMZ | Re-resection, lomustine | 3 × 1010 | No | Wild-type | |
14 | M | 37 | 90 | Resection, re-resection, TMZ, RT | Lomustine | Not infused | No | n/a | |
15 | F | 40 | 100 | Resection, RT/TMZ, aTMZ | Lomustine | 3 × 1010 | No | Mutant | |
16 | M | 55 | 100 | Resection, RT/TMZ, aTMZ | 1010 | No | Wild-type | ||
17 | F | 66 | 90 | Resection, RT/TMZ, aTMZ | Bevacizumab + lomustine | Re-resection | 1010 | Yes | Wild-type |
18 | M | 69 | 90 | Resection, RT/TMZ, | Re-resection, aTMZ | Re-resection | 1010 | Yes | Wild-type |
19 | M | 38 | 80 | Resection, RT/TMZ, aTMZ | Bevacizumab + lomustine | 1010 | No | Wild-type | |
20 | M | 56 | 80 | Resection, RT/TMZ, aTMZ | Re-resection, lomustine | 1010 | No | Wild-type |