Table 2.
All reported adverse events arranged by body systems and toxicity grades.
| Toxicity grade | Total | ||||||
|---|---|---|---|---|---|---|---|
| Body system | 1 | 2 | 3 | 4 | 5 | Missing data | |
| Blood/bone marrow | 95 | 5 | 3 | 103 | |||
| Cardiac general | 5 | 1 | 6 | ||||
| Coagulation | 15 | 15 | |||||
| Constitutional symptoms | 21 | 9 | 3 | 34 | |||
| Dermatology/skin | 6 | 1 | 2 | 9 | |||
| Endocrine | 2 | 1 | 3 | ||||
| Gastrointestinal | 20 | 18 | 2 | 1 (perforation) | 42 | ||
| Hemorrhage/bleeding | 8 | 1 | 9 | ||||
| Infection | 4 | 7 | 1 | 12 | |||
| Lymphatics | 4 | 1 | 5 | ||||
| Metabolic/laboratory | 138 | 19 | 7 | 1 | 165 | ||
| Musculoskeletal/soft tissue | 6 | 5 | 7 | 1 | 19 | ||
| Neurology | 27 | 26 | 14 | 3 | 70 | ||
| Ocular/visual | 2 | 3 | 5 | ||||
| Pain | 22 | 15 | 3 | 40 | |||
| Pulmonary/upper respiratory | 10 | 4 | 2 | 16 | |||
| Renal/genitourinary | 3 | 2 | 2 | 7 | |||
| Syndromes | 1 | 1 | |||||
| Total | 389 | 117 | 48 | 5 | 1 | 1 | 561 |