Skip to main content
. 2022 Feb 11;28(8):1595–1602. doi: 10.1158/1078-0432.CCR-21-1933

Figure 1.

Figure 1. Sunitinib effect in vitro. Proliferation (MTT) assay of GBM and colorectal cancer cell lines incubated with increasing sunitinib concentrations, showing the percentage of proliferation compared with untreated controls (left) and calculated IC50 in micromoles per liter (right). Sunitinib inhibited proliferation of GBM tumor cells in vitro at concentrations 2.8 times higher than achieved intratumorally in patients (Table 1). GBM, glioblastoma; CRC, colorectal cancer.

Sunitinib effect in vitro. Proliferation (MTT) assay of GBM and colorectal cancer cell lines incubated with increasing sunitinib concentrations, showing the percentage of proliferation compared with untreated controls (left) and calculated IC50 in micromoles per liter (right). Sunitinib inhibited proliferation of GBM tumor cells in vitro at concentrations 2.8 times higher than achieved intratumorally in patients (Table 1). GBM, glioblastoma; CRC, colorectal cancer.