Table 1.

Patient characteristics.

	MSS	MSI-H
	(n = 39)	(n = 5)
Age [median (range)]	61 (33–79)	58 (42–67)
Sex (male/female)	26 (67%)/13 (33%)	3 (67%)/2 (33%)
ECOG PS (0/1)	33 (85%)/6 (15%)	4 (80%)/1 (20%)
T category (T3/T4)	34 (87%)/5 (13%)	5 (100%)/0 (0%)
N category (N0/N1–2)	30 (77%)/9 (23%)	3 (67%)/2 (33%)
Stage (II/III)	30 (77%)/9 (23%)	3 (67%)/2 (33%)
Location of primary site from anal verge [median (range)]	7 cm (0–11.5)	6 cm (3–8)
Time from the end of CRT to radical surgery [median (range)]	12.7 weeks (10.9–15.7)	12.7 weeks (11.9–13.4)
Surgery (sphincter sparing/not sphincter sparing/other)	34 (87%)/4 (10%)/1 (3%)a	5 (100%)/0 (0%)/0 (0%)
Adjuvant chemotherapy (performed/not performed)	30 (77%)/9 (23%)	1 (20%)/4 (80%)

^aSurgical resection was not performed in one patient who achieved near-complete clinical response and refused treatment.