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. 2022 Jul 27;12:892923. doi: 10.3389/fonc.2022.892923

Table 6.

Recent findings in literature compared to our results.

study heartD mean [Gy] whole lungD mean [Gy] whole lungV 20 Gy [%] ipsilateral lungD mean [Gy] comment
Xie 2020 (56) 3D-CRT
9.6 ± 3.7
IMRT
7.4 ± 1.3
(n.s.)
3D-CRT
6.7 ± 1.0
IMRT
5.9 ± 0.9
(p < 0.05)
3D-CRT
12.7 ± 2.0
IMRT
7.9 ± 2.6
(p < 0.05)
Supakalin 2018 (58) 3D-CRT
9.5 ± 1.8
IMRT
7.7 ± 1.4
(p < 0.001)
Left- and right-sided breast cancer
Salvestrini 2022 (49) 1.3 - 7.2
without information on technique
Review of mean heart doses in free breathing
Vikström 2018 (54) 3D-CRT
6.2 ± 4.4
6.8 ± 1.2
Saini 2019 (52) 1.88 6.1
Sripathi 2017 (59) 3D-CRT
7.1 ± 3.0
IMRT
11.94 ± 1.73
3D-CRT
16.4 ± 4.4
IMRT
20.2 ± 1.3
3D-CRT
31.4 ± 10.8
IMRT
35.3 ± 7.5
Johansen 2011 (77) 6.5 ± 4.7 13.7 ± 1.9 3D-CRT
Edvardsson 2015 (50) 2.5 5.4 9.1 3D-CRT
Tommasino 2017 (55) 3.5 7.6 IMRT
Kuo 2021 (51) 3.42 ± 1.20 8.81 ± 1.33 Tangential IMRT, medium expiration
Corradini 2018 (62) 2.54 ± 1.40 3.6 ± 0.8 3D-CRT
Haciislamoglu 2019 (65) 3D-CRT
4.41 ± 2.2
IMRT
8.40 ± 2.54
3D-CRT
7.24 ± 2.59
IMRT
12.58 ± 1.75
3D-CRT was planned as field-in-field
Stewart 2008 (78) 3.5 6.5 10 3D-CRT
Taylor 2017 (57) 5.2 5.7 9.0 Systematic review
(2010–2015)
This study 3D-CRT + boost
4.8 ± 2.1
3D-CRT + brachy
3.3 ± 1.6
IMRT + SiB
4.4 ± 1.0
IMRT + brachy
4.5 ± 1.3
3D-CRT + boost
4.2 ± 1.1
3D-CRT + brachy
3.9 ± 0.8
IMRT + SiB
5.9 ± 1.3
IMRT + brachy
5.3 ± 1.6
3D-CRT + boost
6.3 ± 2.0
3D-CRT + brachy
6.1 ± 1.3
IMRT + SiB
8.6 ± 1.9
IMRT + brachy
7.4 ± 1.6
3D-CRT + boost
8.7 ± 2.2
3D-CRT + brachy
7.9 ± 1.1
IMRT + SiB
10.8 ± 1.8
IMRT + brachy
9.9 ± 2.3
Total dose including boost/SiB

n.s., not significant.