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. 2022 Jul 20;14(14):5855–5877. doi: 10.18632/aging.204189

Table 6. GO enrichment analysis of potentially relevant targets of AS-IV anti-SA-AKI.

Ontology ID Description GeneRatio BgRatio p value FDR q value
BP GO:0071216 cellular response to biotic stimulus 30/165 23 6/18670 2.99E-26 1.27E-22 5.26E-23
BP GO:0032496 response to lipopolysaccharide 33/165 330/18670 2.03E-25 3.21E-22 1.32E-22
BP GO:0050727 regulation of inflammatory response 38/165 485/18670 2.26E-25 3.21E-22 1.32E-22
BP GO:0002237 response to molecule of bacterial origin 33/165 343/18670 7.08E-25 7.55E-22 3.11E-22
BP GO:0071222 cellular response to lipopolysaccharide 27/165 205/18670 4.25E-24 3.62E-21 1.49E-21
BP GO:0002446 neutrophil mediated immunity 37/165 499/18670 7.35E-24 5.22E-21 2.16E-21
BP GO:0071219 cellular response to molecule of bacterial origin 27/165 212/18670 1.06E-23 6.48E-21 2.67E-21
BP GO:0072593 reactive oxygen species metabolic process 28/165 284/18670 1.85E-21 9.83E-19 4.06E-19
BP GO:0042119 neutrophil activation 34/165 498/18670 8.71E-21 3.84E-18 1.59E-18
BP GO:0050900 leukocyte migration 34/165 499/18670 9.28E-21 3.84E-18 1.59E-18
CC GO:0031983 vesicle lumen 30/166 339/19717 3.61E-22 1.03E-19 7.75E-20
CC GO:0060205 cytoplasmic vesicle lumen 29/166 338/19717 4.53E-21 6.44E-19 4.87E-19
CC GO:0034774 secretory granule lumen 28/166 321/19717 1.48E-20 1.40E-18 1.06E-18
CC GO:1904813 ficolin-1-rich granule lumen 16/166 124/19717 7.59E-15 5.39E-13 4.07E-13
CC GO:0101002 ficolin-1-rich granule 18/166 185/19717 2.27E-14 1.29E-12 9.74E-13
CC GO:0045121 membrane raft 20/166 315/19717 2.47E-12 1.06E-10 8.03E-11
CC GO:0098857 membrane microdomain 20/166 316/19717 2.62E-12 1.06E-10 8.03E-11
CC GO:0098589 membrane region 20/166 328/19717 5.18E-12 1.84E-10 1.39E-10
CC GO:0005775 vacuolar lumen 14/166 172/19717 2.17E-10 6.83E-09 5.17E-09
CC GO:0090575 RNA polymerase II transcription factor complex 11/166 163/19717 1.37E-07 3.90E-06 2.95E-06
MF GO:0004879 nuclear receptor activity 14/166 47/17697 6.12E-18 1.53E-15 1.02E-15
MF GO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding 14/166 47/17697 6.12E-18 1.53E-15 1.02E-15
MF GO:0003707 steroid hormone receptor activity 13/166 56/17697 3.61E-15 6.02E-13 4.02E-13
MF GO:0019902 phosphatase binding 18/166 185/17697 1.38E-13 1.73E-11 1.16E-11
MF GO:0004175 endopeptidase activity 25/166 427/17697 2.45E-13 2.45E-11 1.64E-11
MF GO:0008236 serine-type peptidase activity 17/166 182/17697 1.33E-12 1.11E-10 7.42E-11
MF GO:0017171 serine hydrolase activity 17/166 186/17697 1.90E-12 1.36E-10 9.07E-11
MF GO:0004252 serine-type endopeptidase activity 16/166 160/17697 2.19E-12 1.37E-10 9.16E-11
MF GO:0019903 protein phosphatase binding 15/166 140/17697 4.01E-12 2.23E-10 1.49E-10
MF GO:0004713 protein tyrosine kinase activity 14/166 134/17697 3.03E-11 1.52E-09 1.02E-09