Table 2.
Association between HSI and risk of T2DM in different models.
| Crude model | Model I | Model II | Model III | Model IV | |
|---|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |
| Continuous | |||||
| HSI (per SD increase) | 1.86 (1.73, 2.00) | 2.09 (1.93, 2.27) | 1.63 (1.42, 1.87) | 1.62 (1.40, 1.87) | 1.62 (1.41, 1.89) |
| Categorical | |||||
| HSI (quintile) | |||||
| Q1 | Ref | Ref | Ref | Ref | Ref |
| Q2 | 2.54 (1.34, 4.83) | 2.04 (1.08, 3.88) | 1.68 (0.88, 3.23) | 1.63 (0.85, 3.13) | 1.66 (0.85, 3.22) |
| Q3 | 4.90 (2.70, 8.90) | 3.47 (1.91, 6.29) | 1.84 (0.98, 3.44) | 1.75 (0.93, 3.29) | 1.82 (0.98, 3.46) |
| Q4 | 9.98 (5.64, 17.66) | 6.78 (3.83, 12.00) | 3.01 (1.60, 5.66) | 2.99 (1.58, 5.64) | 3.19 (1.64, 5.92) |
| Q5 | 15.24 (8.69, 26.72) | 13.05 (7.44, 22.90) | 3.46 (1.75, 6.83) | 3.24 (1.62, 6.47) | 3.48 (1.85, 7.16) |
| P for trend | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Crude model adjusted for none. Model I adjusted for gender and age. Model II adjusted for age, SBP, DBP, FPG, TG, and BMI. Model III adjusted for age, gender, BMI, SBP, DBP, FPG, TG, LDL-C, AST, BUN, smoking status, drinking status, and family history of diabetes. Model IV adjusted for age, gender, BMI, SBP, DBP, FPG, TG, HDL-C, LDL-C, AST, BUN, Scr, smoking status, drinking status, and family history of diabetes. Abbreviations: Ref: reference; CI: confidence interval; HR: hazard ratios.