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. 2022 Aug 8;219(9):e20220038. doi: 10.1084/jem.20220038

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© 2022 Rubin et al.

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Figure 10. — Trajectory analysis of B cell development using FateID. (A and B) UMAP visualizations where fate bias is depicted in color (red = high, blue = low) and represents the probability that a cell will be assigned to a given lineage. The lineage-defining clusters (A) mature IgD B cells and (B) mature IgT B cells have a fate bias of 1 in their respective trajectory maps and a fate bias of 0 in the other. (C and D) Pseudotime plots of the expression of csf1rb, mki67, rag1, rag2, sid1, dntt, ebf3a, pax5, cd79a, igl3v5, and igl1c3 in the (C) mature IgD B cell trajectory and (D) mature IgT B cell trajectory.