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. 2022 Aug 10;5:113. doi: 10.1038/s41746-022-00647-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Network interactions showing links between relapses, metastases and death in breast cancer. b Proportion of distant metastases according to the occurrence or absence of local relapses. c Proportion of deaths according to distant metastasis status. d Distribution plot for relapse-free survival (in months) according to breast cancer subtype. e Proportion plot displaying the relationship between central nervous system (CNS) metastasis and progesterone receptor (PR) status.