Table 2.

Summary of significantly altered gene expressions by spaceflight related to neuronal function.

Gene	p value	Log2 fold Δ	Related molecule function
NRGN	0.0413	−0.16	A Ca2+ dependent intracellular charge transducer.
DLG4	0.00947	−0.279	Postsynaptic density protein associated with glutamatergic receptor signaling.
NLGN2	0.042	−0.306	Postsynaptic cell adhesion molecule mediating inhibitory synapses.
SIN3A	0.0142	−0.43	Involved in cortical neuron differentiation and callosal axon elongation.
RELN	0.00583	−0.535	Regulates microtubule function in neurons and neuronal migration.
SLC2A5	0.0132	−0.623	Fructose transporter found in Purkinje cells and the blood-brain barrier.
KCND1	0.0117	−0.893	K+ voltage-gated channel involved in neurotransmitter release.