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. 2022 Jul 28;13:944183. doi: 10.3389/fimmu.2022.944183

Table 1.

Desired characteristics for novel Tuberculosis immunization approaches.

S. No Desired characteristics
1. Safe to be administered in immunocompromised individuals at risk of developing active TB
2. Expenses associated with regimen and dosage should be reasonable for high burdened developing countries.
3. Immunization strategy must lower the risk of developing active pulmonary TB in adults previously vaccinated with BCG
4. Must protect against M.tb infections for more than 10 years subsequent to immunization
5. Minimum administrations requisite to elicit host protective responses
6. Evaluation of protective immune correlates by employing established assays
7. Must offer greater than 50% protective efficacy against established pulmonary TB