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. 2022 Jul 28;13:944183. doi: 10.3389/fimmu.2022.944183

Table 4.

List of clinical trials evaluating BCG immunization along with diverse immunotherapeutic for efficient medical utility against diverse disease conditions.

BCG vaccine and immunotherapeutic regimen Clinical trial Trial identifier Diseased condition Ref.
Intravesical hyaluronic acid (HA) with BCG Phase 2, randomized, pilot study to examine effect of HA in reducing BCG induced local cytotoxicity NCT02207608 Bladder urothelial cell carcinoma (12)
Tislelizumab in Combination with BCG Phase 2, open-label, single-arm, single center trial to evaluate safety and effectiveness of Tislelizumab along with BCG (TACBIN-01) NCT04922047 High risk urinary bladder cancers (13)
Vitamin D supplementation in adjunct to BCG immunization in infants Randomized, double masked, interventional study to evaluate impact of vitamin D supplement in infants prior to BCG vaccination NCT01288950 Tuberculosis (14)
Vitamin A with BCG Vaccine Phase 4, randomized, double-masked intervention to evaluate the utility of high-dose vitamin A supplementation in infants along with BCG vaccine at birth NCT00168597 Mortality and morbidity in infants (15)
Monoclonal Antibody A1G4 and BCG  Phase 1 intervention to evaluate the efficacy of monoclonal antibody A1G4 along with BCG in cancer patients NCT00003023 * Neuroblastoma, Sarcoma (16)