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. 2022 Jul 28;13:897992. doi: 10.3389/fmicb.2022.897992

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Copyright © 2022 Jing, Chang, Xu, Wang, Wu, Huang, Wang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Experimental design for gut depletion after SAP. (B) Serum amylase levels are significantly increased in the old group compared to the young group. (C) Serum CRP levels are significantly increased in the old group compared to the young group. (D) Heatmap of the CFU (log2) of blood and MLN. (E) Frequency of culture positivity in blood and MLN. CFU in the blood (F) and MLN (G). Expression of AMP genes in the pancreas (H) and ileum (I) of the young group versus the old group (n = 6 per group). ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, ^****p < 0.0001, ns, no significant difference.