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. 2022 Jul 28;13:915784. doi: 10.3389/fimmu.2022.915784

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Copyright © 2022 Zhou, Zhang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of DEGs encoding extracellular proteins (EP-DEGs). (A) Venn diagram of 40 HPA-DEGs obtained based on the intersection between HPA database-extracellular proteins and LN-DEGs. Meanwhile, a Venn diagram of 65 UniProt-DEGs obtained based on the intersection between UniProt database-extracellular proteins and LN-DEGs. Finally, 38 EP-DEGs were screened out based on the intersection between HPA-DEGs and UniProt-DEGs. (B) Volcano plot of EP-DEGs between LN patients and controls. (C) Expression heatmap of screened EP-DEGs.