Table 1.
Demographic characteristics of the study population.
| Induction chemotherapy (N = 159) | Upfront surgery (N = 126) | p-value | |
|---|---|---|---|
| Age (years), mean ± SD | 62.7 ± 9.0 | 66.3 ± 8.3 | 0.58 |
| Sex, number of patients (%) | 0.74 | ||
| * Male | 104 (65.4) | 80 (63.5) | |
| * Female | 55 (74.6) | 46 (36.5) | |
| Main comorbidities, number of patients (%) | 0.51 | ||
| * Cardiac | 66 (41.5) | 73 (57.9) | |
| * Pulmonary | 14 (8.8) | 20 (15.9) | |
| Pulmonary function tests, mean ± SD | 0.96 | ||
| * FEV1% | 88.1 ± 18.9 | 93.5 ± 20.3 | |
| * DLCO/VA | 82.9 ± 20.6 | 90.4 ± 20.7 | |
| Histology, number of patients (%) | 0.54 | ||
| * Adenocarcinoma | 120 (75.5) | 105 (83.3) | |
| * Squamous cell carcinoma | 31 (19.5) | 16 (12.7) | |
| * Adenosquamous | 4 (2.5) | 5 (4.0) | |
| * Neuroendocrine | 3 (1.9) | 0 | |
| * Atypical carcinoid | 1 (0.6) | 0 |
DLCO/VA, diffusing capacity of carbon monoxide divided by the alveolar volume; FEV1%, forced expiratory volume in the first second (measured/predicted %); SD, standard deviation.