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. 2022 Jul 26;26(3):285. doi: 10.3892/mmr.2022.12801

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Copyright: © Luo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Effect of VEGFB downregulation on liver and pancreas. (A) Body weight curve of mice (4–32 weeks). (B) Food intake curve of mice (4–32 weeks) (C and D) Organ coefficient ratio between liver and pancreas in mice. (E) Light microscopic structure of liver and pancreas; a and b: VEGFB+/+ group, c and d: VEGFB-/- group (scale bar, 50 µm; magnification, ×400). (F) Electron microscopic structure of liver and pancreas; a and b: VEGFB+/+ group, c and d: VEGFB-/- group (scale bar, 1 µm; images a and c, ×15,000 magnification; images b and d, ×8,000 magnification). (G and H) Density of mature and immature vesicles. ***P<0.001 vs. VEGFB+/+ group. VEGFB, vascular endothelial growth factor B.