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Effect of VEGFB downregulation on blood glucose balance and insulin resistance. (A) OGTT. (B) Area under the curve in OGTT. (C) IPITT. (D) Area under the curve in IPTT. (E) Fasting insulin. (F) Serum glucagon. (G) HOMA-IR. (H) HOMA-β. *P<0.05 vs. VEGFB+/+ group, **P<0.01 vs. VEGFB+/+ group and ***P<0.001 vs. VEGFB+/+ group. HOMA-IR, insulin resistance index; HOMA-β, pancreatic β-cell secretion index. VEGFB, vascular endothelial growth factor B.
