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. 2022 Jul 28;26(3):290. doi: 10.3892/mmr.2022.12806

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — circ_0005699 attenuates HUVEC apoptosis and inflammation through the miR-450b-5p/NFKB1 axis. (A) Protein expression levels of NFKB1 in different groups of HUVECs, as detected by western blotting. (B) Cell Counting Kit-8 analysis of HUVEC proliferation following different treatments. (C) Apoptotic rate of HUVECs in different groups, as determined by Annexin V/PI double staining and flow cytometry. (D) Protein expression levels of apoptosis-related genes Bcl-2 and Bax. **P<0.01 vs. sh-NC, ##P<0.01 vs. sh-circ_0005699#1. Bcl-2, B-cell lymphoma 2; HUVEC, human umbilical vein endothelial cell; miR, microRNA; NC, negative control; sh, short hairpin RNA.