Figure 1.

Elevated NAT10 expression is associated with poor outcomes in MM patients. (A) NAT10 mRNA levels were significantly increased in MM samples. The signal level of NAT10 (217884_at signaling) was shown on the y-axis (NP, n = 22; MGUS, n = 44; MM, n = 351). (B) IHC staining verified that NAT10 protein level was elevated in MM patient samples and NAT10 expression was positively correlated with Ki67 expression in MM samples (NP, n = 10; MM, n = 20). (C–F) High expression of NAT10 indicted poor overall survival (OS) in TT2 (C), APEX (D), TT3 (E), and HOVON65 (F) cohorts. All data are displayed as mean ± SD; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.