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. Author manuscript; available in PMC: 2022 Aug 11.
Published in final edited form as: J Med Chem. 2018 Oct 11;61(20):9335–9346. doi: 10.1021/acs.jmedchem.8b01249

Figure 4.

Figure 4.

Effect of TAT-TM6 peptides of D2R and A2AR on competition experiments of [3H]YM-09151–2 vs. D2R ligands. Competition curves with increasing concentrations of monovalent 15 (in A) or bivalent 13 (in B) D2R ligands in the absence (black) or in the presence of TAT-TM6 of A2AR (red) or TAT-TM6 of D2R (blue), using membranes from sheep brain striatum. Data are mean±SEM from 3 experiments performed in triplicate.