TABLE 1.
Comparison between the leucopenia profiles on socio-demographics, clinical, pathologic and nutrient in different population.
| Total population | Overall (N = 245) | Adolescent | Adult | ||||
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| Non-LP (n = 64) | LP (n = 79) | p-value | Non-LP (n = 54) | LP (n = 48) | P-value | ||
| Age (years) | 18.00 [14.00, 28.00] | 13.50 [12.00, 16.00] | 14.00 [11.00, 16.00] | 0.545 | 33.50 [25.00, 48.00] | 30.50 [24.75, 44.75] | 0.462 |
| Sex, female, n (%) | 101 (41.2) | 24 (37.5) | 38 (48.1) | 0.27 | 19 (35.2) | 20 (41.7) | 0.64 |
| BMI (kg/m2) | 17.79 [15.00, 20.43] | 17.08 [14.83, 19.75] | 14.79 [14.05, 16.23] | <0.001 | 20.57 [20.31, 20.99] | 18.56 [17.61, 20.31] | <0.001 |
| Nutrient, n (%) | <0.001 | <0.001 | |||||
| Normal | 125 (51.0) | 44 (68.8) | 23 (29.1) | 43 (79.6) | 15 (31.2) | ||
| Mild | 65 (26.5) | 17 (26.6) | 29 (36.7) | 8 (14.8) | 11 (22.9) | ||
| Severe | 55 (22.4) | 3 (4.7) | 27 (34.2) | 3 (5.6) | 22 (45.8) | ||
| PS, n (%) | 0.073 | 0.049 | |||||
| 0 score | 117 (47.8) | 35 (54.7) | 27 (34.2) | 36 (66.7) | 19 (39.6) | ||
| 1 score | 40 (16.3) | 10 (15.6) | 14 (17.7) | 7 (13.0) | 9 (18.8) | ||
| 2 score | 71 (29.0) | 16 (25.0) | 29 (36.7) | 9 (16.7) | 17 (35.4) | ||
| 3 score | 17 (6.9) | 3 (4.7) | 9 (11.4) | 2 (3.7) | 3 (6.2) | ||
| Location, n (%) | 0.592 | 0.845 | |||||
| Distal femur | 186 (75.9) | 43 (67.2) | 58 (73.4) | 46 (85.2) | 39 (81.2) | ||
| Proximal tibia | 30 (12.2) | 12 (18.8) | 10 (12.7) | 4 (7.4) | 4 (8.3) | ||
| Other | 29 (11.8) | 9 (14.1) | 11 (13.9) | 4 (7.4) | 5 (10.4) | ||
| Pathology, n (%) | 0.861 | 0.217 | |||||
| Osteogenic | 164 (66.9) | 44 (68.8) | 51 (64.6) | 38 (70.4) | 31 (64.6) | ||
| Chondrogenic | 44 (18.0) | 9 (14.1) | 12 (15.2) | 9 (16.7) | 14 (29.2) | ||
| Other | 37 (15.1) | 11 (17.2) | 16 (20.3) | 7 (13.0) | 3 (6.2) | ||
| MSTS staging, n (%) | 0.345 | 0.903 | |||||
| IIA | 24 (9.8) | 8 (12.5) | 7 (8.9) | 5 (9.3) | 4 (8.3) | ||
| IIB | 192 (78.4) | 51 (79.7) | 60 (75.9) | 42 (77.8) | 39 (81.2) | ||
| III | 29(11.8) | 5 (7.8) | 12 (15.2) | 7 (13.0) | 5 (10.4) | ||
| CRP (mg/L) | 7.50 [2.63, 12.00] | 8.19 [2.48, 12.38] | 7.55 [3.02, 12.30] | 0.955 | 3.20 [2.32, 6.15] | 10.25 [7.00, 15.33] | <0.001 |
| WBC before (× 109/L) | 6.85 [5.76, 8.20] | 6.99 [5.80, 8.51] | 6.86 [5.88, 8.19] | 0.713 | 6.85 [5.72, 8.08] | 6.70 [5.72, 8.56] | 0.96 |
| Alb (g/L) | 28.90 [27.90, 29.90] | 29.60 [28.28, 39.40] | 28.50 [28.05, 29.70] | 0.013 | 29.30 [28.13, 34.68] | 28.40 [27.00, 29.35] | 0.008 |