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. 2022 Jul 28;12:968547. doi: 10.3389/fonc.2022.968547

Table 4.

The correlation between pathological parameters and GSTM4 expression.

Characteristic Low expression of GSTM4 High expression of GSTM4 p
n 189 190
FIGO stage, n (%) 0.092
Stage I 1 (0.3%) 0 (0%)
Stage II 12 (3.2%) 11 (2.9%)
Stage III 155 (41.2%) 140 (37.2%)
Stage IV 21 (5.6%) 36 (9.6%)
Primary therapy outcome, n (%) 0.998
PD 14 (4.5%) 13 (4.2%)
SD 11 (3.6%) 11 (3.6%)
PR 22 (7.1%) 21 (6.8%)
CR 112 (36.4%) 104 (33.8%)
Race, n (%) 0.020
Asian 7 (1.9%) 5 (1.4%)
Black or African American 6 (1.6%) 19 (5.2%)
White 172 (47.1%) 156 (42.7%)
Age, n (%) 0.714
<=60 106 (28%) 102 (26.9%)
>60 83 (21.9%) 88 (23.2%)
Histologic grade, n (%) 0.056
G1 0 (0%) 1 (0.3%)
G2 29 (7.9%) 16 (4.3%)
G3 157 (42.5%) 165 (44.7%)
G4 0 (0%) 1 (0.3%)
Anatomic neoplasm subdivision, n (%) 0.750
Unilateral 53 (14.8%) 49 (13.7%)
Bilateral 126 (35.3%) 129 (36.1%)
Venous invasion, n (%) 0.046
No 16 (15.2%) 25 (23.8%)
Yes 39 (37.1%) 25 (23.8%)
Lymphatic invasion, n (%) 0.351
No 21 (14.1%) 27 (18.1%)
Yes 54 (36.2%) 47 (31.5%)
Tumor residual, n (%) 0.461
NRD 31 (9.3%) 36 (10.7%)
RD 140 (41.8%) 128 (38.2%)
Tumor status, n (%) 0.284
Tumor free 32 (9.5%) 40 (11.9%)
With tumor 139 (41.2%) 126 (37.4%)
Age, meidan (IQR) 58 (50, 68) 59 (52, 68) 0.345