Ligand heavy atoms RMSD analysis for studies compounds in the active site of SARS-CoV-2 RdRp during the production run.

	Control	HA1	HA2	HA3	HA4	HA5
Average RMSD (nm)	0.378	1.030	1.038	0.799	0.940	1.025
Standard deviation	0.041	0.440	0.121	0.071	0.181	0.235
Percent standard deviation (%)	10.80	42.68	11.63	8.83	19.28	22.89