Supplementary Table 1.

Statistical Analysis of Experimental Results

	Figure 1A Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1.00	0.12	.001
H/R	1	3	0.41	0.05
	Figure 1B Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	1.00	0.13	<0
miR-615-3p	1	3	11.00	1.10
	Figure 1C Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1.80	0.20	< 0
H/R	1	3	0.90	0.11
NC mimics	1	3	0.80	0.10	.001
miR-615-3p	1	3	1.60	0.18
	Figure 1E Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	5.41	0.55	< 0
H/R	1	3	15.81	0.89
NC mimics	1	3	17.11	0.48	< 0
miR-615-3p	1	3	9.82	0.85
	Figure 1G Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	2.20	0.23	.001
H/R	1	3	4.50	0.51
NC mimics	1	3	4.70	0.52	.015
miR-615-3p	1	3	3.30	0.35
	Figure 1H Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	60.00	6.20	.001
H/R	1	3	35.00	3.62
NC mimics	1	3	36.00	3.70	.005
miR-615-3p	1	3	56.00	5.66
	Figure 1I Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	2.20	0.24	.001
H/R	1	3	4.20	0.45
NC mimics	1	3	4.40	0.46	.038
miR-615-3p	1	3	3.30	0.40
	Figure 2A Experimental Results
PSMD11	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1.00	0.11	.372
H/R	1	3	0.92	0.09
ZNF626	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1.00	0.10	.294
H/R	1	3	0.90	0.10
ITSN1	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1.00	0.09	.681
H/R	1	3	0.96	0.11
MEF2A	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1.00	0.11	< 0
H/R	1	3	3.33	0.35
USP44	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1.00	0.09	.336
H/R	1	3	1.10	0.13
TOMM7	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1.00	0.12	.839
H/R	1	3	0.98	0.10
	Figure 2E Experimental Results
Wt	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	1.00	0.11	.001
miR-615-3p	1	3	0.43	0.05
Mut	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	1.00	0.09	.72
miR-615-3p	1	3	0.97	0.10
	Figure 2F Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	1.00	0.11	.002
miR-615-3p	1	3	0.46	0.05
	Figure 3A Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	1.00	0.10
miR-615-3p	1	3	0.43	0.05	.007
miR-615-3p+MEF2A	1	3	2.14	0.22	< 0
	Figure 3C Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	0.50	0.06
miR-615-3p	1	3	1.05	0.11	< 0
miR-615-3p+MEF2A	1	3	0.66	0.07	.003
	Figure 3E Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	14.71	0.62
miR-615-3p	1	3	6.04	0.37	< 0
miR-615-3p+MEF2A	1	3	13.31	0.40	< 0
	Figure 3G Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	4.20	0.45
miR-615-3p	1	3	2.50	0.03	.002
miR-615-3p+MEF2A	1	3	3.70	0.38	.012
	Figure 3H Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	26.10	2.65
miR-615-3p	1	3	44.30	4.45	.002
miR-615-3p+MEF2A	1	3	31.00	3.89	.011
	Figure 3I Experimental Results
	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
NC mimics	1	3	3.90	0.40
miR-615-3p	1	3	2.20	0.34	.003
miR-615-3p+MEF2A	1	3	3.50	0.36	.012
	Figure 4A Experimental Results
p-PI3K/PI3K	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1.00	0.12
H/R	1	3	2.34	0.17	< 0
NC mimics	1	3	2.37	0.20
miR-615-3p	1	3	1.35	0.11	0
miR-615-3p+MEF2A	1	3	1.89	0.15	.01
p-Akt/Akt	n (Trials/Sample Size)	r (Replication Size)	Mean	Standard Deviation	P
Control	1	3	1	0.1
H/R	1	3	2.69	0.31	< 0
NC mimics	1	3	2.75	0.29
miR-615-3p	1	3	1.30	0.11	0
miR-615-3p+MEF2A	1	3	2.05	0.17	.011