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. 2022 Jul 28;13:931014. doi: 10.3389/fneur.2022.931014

Table 2.

Variables whose isolated change does not allow diagnosis of progression.

Statement Consensus in favor
Grade of agreement Grade of recommendation
(%) a Median (%) b Median
A confirmed worsening by 2 points in any functional system (except the visual system) 67 Disagree NC According to clinical criteria/optional
A confirmed worsening by 2 points in any functional system (except the visual system) with a disease duration <10 years 67 Disagree NC According to clinical criteria/optional
A confirmed 20% time increase in:
 the 25FTW 93 Disagree 93 Not recommended
 the 9HPT 100 Disagree NC Not recommended
 the 2MWT 93 Disagree 66 Not recommended
Experiencing repeated falls 93 Disagree NC Not recommended
A confirmed 20% reduction in the SDMT 93 Agree 67 Recommended
A confirmed 20% worsening in at least two subtests of the BRB-N or BICAMS battery 87 Agree 80 Recommended
a

Sum of the percentages of responses obtained for “Totally disagree” and “Disagree.” If no consensus was reached (i.e., <66%) NC is shown.

b

Sum of the percentages of responses obtained for “Not recommended” and “Depending on availability.” If no consensus was reached (i.e., <66%) NC is shown.