Table 3.
Variables whose isolated change indicates that more accurate progression diagnostic tools should be used.
| Statement | Consensus in favor | |||
|---|---|---|---|---|
| Grade of agreement | Grade of recommendation | |||
| (%) a | Median | (%) b | Median | |
| A confirmed reduction from 500 to 300 meters in a patient capable of wandering 500 meters or more without help or rest | 100 | Totally agree | 93 | Essential |
| Transition from walking independently to needing any kind of support or help to walk | 100 | Totally agree | 100 | Essential |
| Changes in the QoL questionnaires | 80 | Agree | 73 | Recommended |
| A worsening of spasticity | 87 | Agree | 73 | Recommended |
| A change in the degree of brain atrophy | 93 | Totally agree | 93 | Recommended |
| A change in the degree of spinal atrophy | 93 | Totally agree | 93 | Recommended |
Sum of the percentages of responses obtained for “Totally agree” and “Agree.” If no consensus was reached (i.e., <66%) NC is shown.
Sum of the percentages of responses obtained for “Recommended” and “Essential.” If no consensus was reached (i.e., <66%) NC is shown.