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. 2022 Jul 28;13:931014. doi: 10.3389/fneur.2022.931014

Table 3.

Variables whose isolated change indicates that more accurate progression diagnostic tools should be used.

Statement Consensus in favor
Grade of agreement Grade of recommendation
(%) a Median (%) b Median
A confirmed reduction from 500 to 300 meters in a patient capable of wandering 500 meters or more without help or rest 100 Totally agree 93 Essential
Transition from walking independently to needing any kind of support or help to walk 100 Totally agree 100 Essential
Changes in the QoL questionnaires 80 Agree 73 Recommended
A worsening of spasticity 87 Agree 73 Recommended
A change in the degree of brain atrophy 93 Totally agree 93 Recommended
A change in the degree of spinal atrophy 93 Totally agree 93 Recommended
a

Sum of the percentages of responses obtained for “Totally agree” and “Agree.” If no consensus was reached (i.e., <66%) NC is shown.

b

Sum of the percentages of responses obtained for “Recommended” and “Essential.” If no consensus was reached (i.e., <66%) NC is shown.