Fig. 1.

Clinical presentation and diagnostic findings in patients with epidermolysis bullosa acquisita (EBA). (a) Clinical picture of a patient with inflammatory EBA with erosions on the back. (b) Direct immunofluorescence (IF) microscopy of a perilesional biopsy of a patient with EBA showing linear deposition of immunoglobulin G (IgG) at the dermal–epidermal junction with a u-serrated pattern. (c) Indirect IF microscopy on 1 M NaCl-split human skin of an EBA patient’s serum reveals linear binding of IgG serum autoantibodies at the floor of the artificial blister.