Table II.
Sensitivities of the serological tests calculated individually for Japanese and European patients
| Patients | Indirect IF on SSS (blister floor) n (%) | NC1 BIOCHP® mosaic n (%) | NC1 ELISA n (%) | NC1/NC2 ELISA n (%) | FL Col7 ELISA n (%) | Dermal extract IB (Col7) n (%) | NC1 IB n (%) |
|---|---|---|---|---|---|---|---|
| Japanese EBA sera (n = 52) | 51 (98.1) | 48 (92) | 47 (90.4) | 50 (96.2) | 39 (75) | 48 (92) | 50 (96.2) |
| European EBA sera (n = 49) | 46 (93.9) | 41 (85.7) | 37 (75.5) | 39 (79.6) | 41 (83.7) | 41 (83.7) | 45 (91.8) |
EBA: epidermolysis bullosa acquisita; NC: non-collagenous domain; IF: immunofluorescence; FL: full-length; IB: immunoblot.