Table II.
Skin cancer | Non-melanoma skin cancer | Cutaneous melanoma | |||||||
---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | HR | 95% CI | p-value | |
Model 1a | |||||||||
Treatment with UVB phototherapy | 1.236 | 0.713–2.141 | 0.45 | 1.260 | 0.713–2.225 | 0.43 | 0.956 | 0.112–8.199 | 0.97 |
Model 2b | |||||||||
Treatment with UVB phototherapy | 1.255 | 0.724–2.176 | 0.42 | 1.279 | 0.724–2.261 | 0.40 | 0.969 | 0.113–8.337 | 0.98 |
Age, years | 1.048 | 1.028–1.069 | < 0.001 | 1.046 | 1.026–1.067 | < 0.001 | 1.072 | 0.995–1.154 | 0.07 |
Male sex | 1.679 | 1.057–2.666 | 0.03 | 1.574 | 0.977–2.535 | 0.06 | 4.398 | 0.511–37.869 | 0.18 |
Model 3c | |||||||||
Treatment with UVB phototherapy | 1.066 | 0.584–1.944 | 0.84 | 1.067 | 0.571–1.996 | 0.84 | 1.009 | 0.115–8.879 | 0.99 |
Age, years | 1.065 | 1.041–1.089 | < 0.001 | 1.061 | 1.037–1.086 | < 0.001 | 1.117 | 1.018–1.224 | 0.02 |
Male sex | 1.738 | 1.076–2.808 | 0.02 | 1.627 | 0.992–2.669 | 0.05 | 4.208 | 0.482–36.717 | 0.19 |
Outdoor occupation | 2.104 | 1.293–3.423 | 0.003 | 1.974 | 1.186–3.285 | 0.01 | 4.451 | 0.846–23.417 | 0.08 |
High UV indexd | 1.110 | 0.695–1.773 | 0.66 | 1.257 | 0.772–2.048 | 0.36 | 0.208 | 0.023–1.846 | 0.16 |
Organ transplantation | 5.911 | 3.178–10.995 | < 0.001 | 5.389 | 2.815–10.314 | < 0.001 | 17.769 | 2.021–156.189 | 0.01 |
Hydrochlorothiazide | 1.368 | 0.861–2.175 | 0.19 | 1.324 | 0.816–2.150 | 0.26 | 2.006 | 0.396–10.160 | 0.40 |
Model 1: Univariate Cox proportional hazards model adjusted for treatment with UVB phototherapy.
Model 2: Multivariate Cox for the variable in model 1 and for age and sex.
Model 3: Multivariate Cox proportional hazards model adjusted for all variables in index, organ transplantation, and the prescription of hydrochlorothiazide.
Mean UV index >6 at location of residence.
CI: confidence interval; HR: hazard ratio.