Table III.
Skin cancer | Non-melanoma skin cancer | Cutaneous melanoma | |||||||
---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | HR | 95% CI | p-value | |
Model 1a Number of UVB phototherapy treatments |
1.002 | 0.985–1.019 | 0.85 | 0.998 | 0.974–1.023 | 0.90 | 1.010 | 0.989–1.031 | 0.35 |
Model 2b Number of UVB phototherapy treatments |
1.001 | 0.984–1.017 | 0.95 | 0.998 | 0.974–1.022 | 0.84 | 1.009 | 0.988–1.031 | 0.40 |
Age, years | 1.048 | 1.028–1.069 | < 0.001 | 1.046 | 1.026–1.067 | <0.001 | 1.071 | 0.995–1.153 | 0.07 |
Male sex | 1.676 | 1.055–2.662 | 0.03 | 1.571 | 0.976–2.531 | 0.06 | 4.525 | 0.519–39.416 | 0.17 |
Model 3c Number of UVB phototherapy treatments |
1.001 | 0.984–1.018 | 0.90 | 0.998 | 0.974–1.022 | 0.87 | 1.010 | 0.987–1.033 | 0.42 |
Age, years | 1.065 | 1.041–1.089 | < 0.001 | 1.061 | 1.037–1.086 | <0.001 | 1.115 | 1.017–1.222 | 0.02 |
Male sex | 1.739 | 1.076–2.810 | 0.02 | 1.629 | 0.993–2.672 | 0.05 | 4.345 | 0.491–38.451 | 0.19 |
Outdoor occupation | 2.102 | 1.292–3.422 | 0.003 | 1.964 | 1.180–3.269 | 0.01 | 4.674 | 0.874–24.991 | 0.07 |
High UV indexd | 1.111 | 0.696–1.775 | 0.66 | 1.257 | 0.772–2.047 | 0.36 | 0.209 | 0.023–1.865 | 0.16 |
Organ transplantation | 5.896 | 3.171–10.962 | < 0.001 | 5.379 | 2.811–10.293 | <0.001 | 17.139 | 1.961–149.772 | 0.01 |
Hydrochlorothiazide | 1.373 | 0.865–2.181 | 0.18 | 1.328 | 0.819–2.154 | 0.25 | 2.060 | 0.407–10.411 | 0.38 |
Model 1: Univariate Cox proportional hazards model adjusted for the number of UVB phototherapy treatments received by each patient.
Model 2: Multivariate Cox proportional hazards model adjusted for the variable in model 1 and for age and sex.
Model 3: Multivariate Cox proportional hazards model adjusted for all variables in model 2 and for occupation, high UV index, organ transplantation, and the prescription of hydrochlorothiazide.
Mean UV index > 6 at location of residence.
The number of UVB phototherapy treatments was analysed as a continuous variable, and the HR indicates the effect of every 1 additional UVB phototherapy treatment received by the patient.
CI: confidence interval; HR: hazard ratio.