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. 2022 Jul 28;12:941752. doi: 10.3389/fonc.2022.941752

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Copyright © 2022 Chen, Yan, Lin, Chen, Chen and Lin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CT-guided RFA for rabbit lung VX2 tumor with MR and pathological findings. CT showed a VX2 tumor located in right lower lobe with 12 mm in diameter (A, arrow). The pre-ablation MR scan of the tumor showed hyperintensity on T2WI and isointensity on T1WI before RFA (B, C, arrow). Radiofrequency electrode was gradually punctured into the tumor under CT guidance (D). GGO surrounding the lesion with 5 mm beyond was displayed immediately after RFA on CT (E). Immediately after RFA, MR showed short T1 and short T2 signals in the central area and patchy iso-T1 and long T2 signals in the periphery (F, G arrow). Pathology showed coagulative necrosis of the ablation foci, with peripheral hemorrhage and inflammatory reaction zone (H). RFA, radiofrequency ablation; T2WI, T2-weighted image; T1WI, T1-weighted image; GGO, ground-glass opacity.