Table 5.
Summary of findings from studies that included statistical comparisons with respect to transmission of SARS for Specific AGMPs*
| AGMP | AGMP activity | Author | Study design | Sample size | Odds ratioa (95%CI) |
|---|---|---|---|---|---|
| Airway Suctioning | After intubation | Loeb [63] | Retrospective cohort |
AGMP: n = 19 Control: n = 13 |
0.68 (0.21 to 2.26) |
| Before intubation | Loeb [63] | Retrospective cohort |
AGMP: n = 4 Control: n = 28 |
4.2 (1.58 to 11.14) | |
| Endotracheal aspirate | Loeb [63] | Retrospective cohort |
AGMP: n = 12 Control: n = 20 |
1.0 (0.29 to 3.45) | |
| Present in room after intubation | Raboud [55] | Retrospective cohort |
AGMP: n = 165 Control: n = 459 |
1.63 (0.97 to 2.73) | |
| Present in room before intubation | Raboud [55] | Retrospective cohort |
AGMP: n = 113 Control: n = 511 |
1.78 (0.97 to 3.29) | |
| Bronchoscopy | Performed | Loeb [63] | Retrospective cohort |
AGMP: n = 2 Control: n = 30 |
2.14 (0.46 to 9.9) |
| CPR | Performed | Loeb [63] | Retrospective cohort |
AGMP: n = 3 Control: n = 29 |
AGMP cases: 0 Control cases: 8 p = 0.55 |
| Present in room during compressions | Raboud [55] | Retrospective cohort |
AGMP: n = 9 Control: n = 615 |
6.39 (3.27 to 12.5) | |
| Present in room during defibrillation | Raboud [55] | Retrospective cohort |
AGMP: n = 4 Control: n = 620 |
15.73 (5.27 to 46.9) | |
| Close proximity (< 1 m) | Liu [62] | Case–control |
AGMP: n = 15 Control: n = 462 |
AGMP cases: 5 Control cases: 51 p = 0.02 |
|
| Intubation | Performed | Chen [65] | Retrospective cohort |
AGMP: n = 33 Control: n = 715 |
8.03 (3.9 to 16.56) |
| Performed or assisted | Fowler [64] | Retrospective cohort |
AGMP: n = 14 Control: n = 62 |
RR: 13.29 (2.99 to 59.04) | |
| Performed | Loeb [63] | Retrospective cohort |
AGMP: n = 4 Control: n = 28 |
4.2 (1.58 to 11.14) | |
| Present in room | Raboud [55] | Retrospective cohort |
AGMP: n = 144 Control: n = 480 |
2.92 (1.7 to 5.03) | |
| Close proximity (< 1 m) | Liu [62] | Case–control |
AGMP: n = 12 Control: n = 465 |
AGMP cases: 6 Control cases: 45 p = < 0.001 |
|
| Performed/Assisted | Teleman [58] | Case–control |
AGMP: n = 6 Control: n = 80 |
1.5 (0.4 to 5.4) | |
| Performed | Pei [60] | Case–control |
AGMP: n = 37 Control: n = 406 |
30.79 (7.91 to 119.84)b | |
| Manual Ventilation | Performed | Loeb [63] | Retrospective cohort |
AGMP: n = 7 Control: n = 25 |
1.19 (0.3 to 4.65) |
| Present in room during on-invasive ventilation | Raboud [55] | Retrospective cohort |
AGMP: n = 109 Control: n = 515 |
1.37 (0.14 to 13.1) | |
| Present in room during manual ventilation after intubation | Raboud [55] | Retrospective cohort |
AGMP: n = 120 Control: n = 504 |
1.83 (1.09 to 3.07) | |
| Present in room during manual ventilation before intubation | Raboud [55] | Retrospective cohort |
AGMP: n = 118 Control: n = 506 |
2.68 (1.34 to 5.35) | |
| Present > 30 min during use of NPPV | Scales [59] | Retrospective cohort |
AGMP: n = 22 Control: n = 9 |
105 (3 to 3035) | |
| Mechanical Ventilation | Present in room | Raboud [55] | Retrospective cohort |
AGMP: n = 236 Control: n = 388 |
1.06 (0.49 to 2.3) |
| Nebulizer | Performed | Loeb [63] | Retrospective cohort |
AGMP: n = 5 Control: n = 27 |
3.24 (1.11 to 9.42) |
| Oxygen administration | Manipulated BiPAP mask | Loeb [63] | Retrospective cohort |
AGMP: n = 6 Control: n = 26 |
2.6 (0.8 to 7.99) |
| Manipulated oxygen mask | Loeb [63] | Retrospective cohort |
AGMP: n = 14 Control: n = 18 |
9 (1.25 to 64.89) | |
| Present in room during procedure | Raboud [55] | Retrospective cohort |
AGMP: n = 108 Control: n = 516 |
0.67(0.43 to 1.04) | |
| Performed | Teleman [58] | Case–control |
AGMP: n = 17 Control: n = 69 |
1.0 (0.3 to 2.8) | |
| Tracheostomy | Performed | Chen [65] | Retrospective cohort |
AGMP: n = 17 Control: n = 731 |
4.15 (1.5 to 11.5) |
Bolded estimates represent statistically significant results (p < 0.05). Details pertaining to patients and settings and studies that only reported count data but no statistical comparisons can be found in Table 2
AGMP aerosol-generating medical procedure; CI confidence interval; RR risk ratio
aOdds Ratio unless otherwise specified
bAdjusted odds ratio reported because unadjusted odds ratios could not be found