Table 1.
Characteristics of cases of patients infected with Klebsiella pneumoniae NDM-1 and controls.
| Variable | Cases N = 139 (%) | Controls N = 486 (%) | OR | p |
|---|---|---|---|---|
| Gender, males/females | 86 (61.9)/53 (38.1) | 324 (66.7)/162 (33.3) | 1.233 | 0.171 |
| Age (years) | 41.17 ± 22.74 | 42.04 ± 25.11 | 0.714 | |
| Diabetes mellitus | 34 (24.5) | 111 (22.8) | 1.094 | 0.384 |
| Hypertension | 40 (28.8) | 139 (28.6) | 1.009 | 0.523 |
| Neurological disease | 59 (42.4) | 154 (31.7) | 1.590 | 0.013 |
| Cardiac disease | 33 (23.7) | 80 (16.5) | 1.580 | 0.035 |
| Lung disease | 46 (33.1) | 151 (31.1) | 1.097 | 0.361 |
| Liver disease | 7 (5) | 28 (5.8) | 0.867 | 0.467 |
| Biliary disease | 5 (3.6) | 25 (5.1) | 0.688 | 0.309 |
| Acute renal failure | 54 (38.8) | 75 (15.4) | 3.481 | <0.001* |
| Chronic renal failure | 15 (10.8) | 58 (11.9) | 0.893 | 0.421 |
| Transplant | 5 (3.6) | 8 (1.6) | 2.229 | 0.140 |
| Immunosuppression | 21 (15.1) | 55 (11.3) | 1.395 | 0.145 |
| Alcoholism | 24 (17.3) | 125 (25.7) | 0.603 | 0.023 |
| Cancer | 6 (4.3) | 38 (7.8) | 0.532 | 0.105 |
| Previous hospitalization (6 months) | 48 (34.5) | 155 (31.9) | 1.126 | 0.313 |
| Previous surgery (1 month) | 18 (12.9) | 43 (8.8) | 1.533 | 0.103 |
| Glasgow coma scale | 11.46 ± 3.9 | 13.36 ± 3.12 | <0.001* | |
| SOFA | 4.37 ± 4.08 | 2.58 ± 3.02 | <0.001* | |
| APACHE II score | 4.37 ± 4.08 | 2.58 ± 3.02 | <0.001* | |
| Creatinine | 1.34 ± 2.02 | 2.4 ± 9.14 | 0.201 | |
| Alkaline phosphatase | 171.8 ± 138.1 | 123.95 ± 104.4 | <0.001* | |
| Procalcitonin | 10.31 ± 28.14 | 5.61 ± 15.08 | 0.103 | |
| C-reactive protein | 167.34 ± 94.8 | 82.83 ± 91.3 | <0.001* | |
| Days of hospital stay | 43.05 ± 31.3 | 15.58 ± 14.4 | <0.001* | |
| Mortality risk | 26.14 ± 19.39 | 17.97 ± 14.8 | <0.001* | |
| Outcome | 89 (64) | 445 (91.6) | 6.098 | <0.001* |
| Improvement Death |
50 (36) | 41 (8.4) |
Values are expressed as mean ± SD or n (%).
SOFA, Sequential Organ Failure Assessment score; APACHE, Acute Physiology and Chronic Health Evaluation.
*p-value is less than 0.05.