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. 2022 Jul 28;12:867347. doi: 10.3389/fcimb.2022.867347

Table 1.

Characteristics of cases of patients infected with Klebsiella pneumoniae NDM-1 and controls.

Variable Cases N = 139 (%) Controls N = 486 (%) OR p
Gender, males/females 86 (61.9)/53 (38.1) 324 (66.7)/162 (33.3) 1.233 0.171
Age (years) 41.17 ± 22.74 42.04 ± 25.11 0.714
Diabetes mellitus 34 (24.5) 111 (22.8) 1.094 0.384
Hypertension 40 (28.8) 139 (28.6) 1.009 0.523
Neurological disease 59 (42.4) 154 (31.7) 1.590 0.013
Cardiac disease 33 (23.7) 80 (16.5) 1.580 0.035
Lung disease 46 (33.1) 151 (31.1) 1.097 0.361
Liver disease 7 (5) 28 (5.8) 0.867 0.467
Biliary disease 5 (3.6) 25 (5.1) 0.688 0.309
Acute renal failure 54 (38.8) 75 (15.4) 3.481 <0.001*
Chronic renal failure 15 (10.8) 58 (11.9) 0.893 0.421
Transplant 5 (3.6) 8 (1.6) 2.229 0.140
Immunosuppression 21 (15.1) 55 (11.3) 1.395 0.145
Alcoholism 24 (17.3) 125 (25.7) 0.603 0.023
Cancer 6 (4.3) 38 (7.8) 0.532 0.105
Previous hospitalization (6 months) 48 (34.5) 155 (31.9) 1.126 0.313
Previous surgery (1 month) 18 (12.9) 43 (8.8) 1.533 0.103
Glasgow coma scale 11.46 ± 3.9 13.36 ± 3.12 <0.001*
SOFA 4.37 ± 4.08 2.58 ± 3.02 <0.001*
APACHE II score 4.37 ± 4.08 2.58 ± 3.02 <0.001*
Creatinine 1.34 ± 2.02 2.4 ± 9.14 0.201
Alkaline phosphatase 171.8 ± 138.1 123.95 ± 104.4 <0.001*
Procalcitonin 10.31 ± 28.14 5.61 ± 15.08 0.103
C-reactive protein 167.34 ± 94.8 82.83 ± 91.3 <0.001*
Days of hospital stay 43.05 ± 31.3 15.58 ± 14.4 <0.001*
Mortality risk 26.14 ± 19.39 17.97 ± 14.8 <0.001*
Outcome 89 (64) 445 (91.6) 6.098 <0.001*
Improvement
Death
50 (36) 41 (8.4)

Values are expressed as mean ± SD or n (%).

SOFA, Sequential Organ Failure Assessment score; APACHE, Acute Physiology and Chronic Health Evaluation.

*p-value is less than 0.05.